The railway lines between Swindon and Gloucester have been closed.
A train collided with a car on a level crossing in Frampton Mansell at around 3.10pm.
British Transport Police say a man has been killed in the crash.
The car was struck by the Great Western Railway’s London Paddington to Cheltenham Spa service. There are no other reported injuries.
At present, officers are currently examining the scene to establish the circumstances which led to the man’s car being struck.
The Rail Accident Investigation Branch have been notified of this incident.
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