Police are advising motorists to avoid to B4040 near Malmesbury following a crash.
Three vehicles were involved in the collision at around 5pm today, with police officers reopening one land past the scene for a short time before recovery trucks arrive.
The incident is between the Easton Grey and Pinkney villages.
A spokesperson for Wiltshire Police said: “When the recovery vehicles arrive we will need to close the road again, please avoid the area if possible for the foreseeable.”