The A350 has been closed in both directions following a crash in Chippenham.
Emergency services were called to a road traffic collision at around 5.30pm today (Tuesday).
Police, fire and ambulance are on scene – but further details are unknown at this time.
The road – between Junction 17 and the Kington Langley junction – is expected to remain shut for several hours.
A spokesperson for Wiltshire Police said: “The A350 has been closed south of junction 17 to the traffic lights with Kington Langley following a road traffic collision.
“The road is likely to be closed southbound for some time. Please find alternative routes.”