The A361 near Lechlade has been closed after a serious road traffic collision.
Emergency services were called to the scene in the Broughton Poggs area at around 8.30am this morning (Monday).
A vehicle is believed to have left the carriageway and hit a tree – leaving at least one person with serious injuries.
A spokesperson for Thames Valley Police said: “The A361 near to Filkins towards Lechlade is currently closed in both directions due to a serious road traffic collision.
“It is likely to remain closed for some time.
“We would urge drivers to please find alternative routes.”
